Theatre review: Marianne.

Marianne. Wimbledon Studio. 15 May 2010.

This play about a couple who lose their only child may not sound like a good way to spend an evening. However, the play is both funny, meaningful and painfull in it’s truthfullness.

When Marianne dies in a freak accident, Cath and David lose a daughter. Allie loses a best friend and Ash gains a heart. They all deal with their grief in different ways. Cath ( Played by Lynn Howes. Who gives a stunning performance ) looks for some kind of meaning in the pointlessness of her daughters death. She longs to understand death and have some kind of closure. Taking her to London and the boy ( Ash. Played by Simon-Anthony Rhoden. ) who received her daughters heart. The clash in culture and in greif – in both life and death – is well written and really makes you think.

David is stoic. Trying to move on, tending to his flowers. All the while dealing with his wife’s, more obvious grief. She uses him as an emotional punching bag. He loves her so he doesn’t mind. David is played by Leighton Pugh. All the cast are amazing. The top of their field.

Allie, ( Natasha Campbell. ) who was Marianne’s best friend is a rebellious teenager who things she is grown up. She visits the couple to try and re-connect with her best friend. She feels they are the only people she can talk to. She is falling in love for the first time and everything is a big deal. Across generations, bonds are made and the healing begins.

The play is beautiful and poignant. The kind of play that makes you think and, more importantly, feel. Cath cannot come to terms with the death of her daughter. She is stuck in a limbo. Thinking her husband has healed while he dies inside. In the end, with help from Allie and Ash they both learn and move on. Their marriage is saved. Life begins again.

This play was written by Anna Jordan. I would keep an eye on her. She is definitely going places.

Leighton PuLeighton Puggh, Lynn Howes, Natasha Campbell and Simon-Anthony Rhoden

Sloth Sanctuary {Misc-uity}

Sloths are the only animals (apart from dolphins) that always have a smile on their faces. This cute video was filmed at Aviaros del Caribe; a sloth sanctuary in Costa Rica: the world’s only sloth orphanage. “Baby two- and three-toed sloths, whose mother’s have either been run over or zapped by power lines are brought to the sanctuary and looked after by Judy Arroyo.”

Watch the video, my favourite part is about 17 seconds in. So cute!

For more sloth photos and videos, visit amphibian avenger’s blog, or follow her on twitter. For more on the sanctuary go to slothrescue.org.

Researchers create the first synthetic self-replicating living cell

Researchers at the J. Craig Venter Institute published results yesterday describing the successful construction of the first self-replicating, synthetic bacterial cell. They’ve christened it Mycoplasma mycoides JCVI-syn1.0 (I like to call it Mike). Working from that idea that “In essence, scientists are digitizing biology by converting the A, C, T, and G’s of the chemical makeup of DNA into 1’s and 0’s in a computer. But can one reverse the process and start with 1’s and 0’s in a computer to define the characteristics of a living cell?”; Venter calls it ‘the first self-replicating species we’ve had on the planet whose parent is a computer’.

The scientific team headed by Drs. Craig Venter, Hamilton Smith and Clyde Hutchison spent 15 years working on the first synthetic bacterial cell. Always conscious that the work they were doing was monumental; throughout the course of this work, the team contemplated, discussed, and engaged in outside review of the ethical and societal implications of their work. JCVI say “The ability to routinely write the software of life will usher in a new era in science, and with it, new products and applications such as advanced biofuels, clean water technology, and new vaccines and medicines.”

The genomes were designed on the computer, chemically made in the laboratory and transplanted into a recipient cell to produce a new self-replicating cell controlled only by the synthetic genome.The team have also designed and inserted what they’ve called watermarkes into the cell that don’t create any proteins but contain a hidden code. These are specifically designed segments of DNA that use the “alphabet” of genes and proteins that enable the researcher to spell out words and phrases. The watermarks are an essential means to prove that the genome is synthetic and not native, and to identify the laboratory of origin. Encoded in the watermarks is a new DNA code for writing words, sentences and numbers. In addition to the new code there is a web address to send emails to if you can successfully decode the new code, the names of 46 authors and other key contributors and three quotations: “TO LIVE, TO ERR, TO FALL, TO TRIUMPH, TO RECREATE LIFE OUT OF LIFE.” – JAMES JOYCE; “SEE THINGS NOT AS THEY ARE, BUT AS THEY MIGHT BE.”-A quote from the book, “American Prometheus”; “WHAT I CANNOT BUILD, I CANNOT UNDERSTAND.” – RICHARD FEYNMAN.

Scanning electron micrographs of M. mycoides JCVI-syn1

Incase you’re worrying that the new cell’s going to escape into the outside world JCVI say that “researchers will be able to engineer synthetic bacterial cells so they cannot live outside of the lab or other production environments. This is done by, for example, ensuring that these organisms have built in dependencies for certain nutrients without which they cannot survive. They can also be engineered with so called “suicide genes” that kick in to prevent the organism from living outside of the lab or environment in which they were grown. ”

The potential for this research and the next steps for JVCI’s researchers are exciting. “The team is now ready to build more complex organisms with useful properties.  For example, many, including scientists at SGI, are already using available sequencing information to engineer cells that can produce energy, pharmaceuticals, and industrial compounds, and sequester carbon dioxide.”

Venter maintains that it’s not a second genesis as they’ve not created life “from scratch” but as they’ve used an existing cell; they’ve created a new species. This new cell has around 1 million base pairs into a coherent genome.  By comparison, the human genome contains more than 3 billion pairs, so don’t don’t worry about synthetic mammals any time soon.

[JCVI]

Is it Snake Oil? – Interactive Infographic

It’s hard to know what’s good and what’s guff, should you be taking vitamin supplements? Will my anti-oxident rosehip cranberry echinacia lavender infusion cure my indecision or should I plump for a green tea? Will that weight loss suppliment advertised on Facebook actually work? Afterall, it is on Facebook, so it must be true?! There’s so much confusing and conflicting information what we really need is someone to take all the evidence and put it into some sort of pretty picture.
If there’s one thing the people behind Information is Beatiful have proved that interactive graphics definately improve my attention span.
The creators have this to say about the image and information they used: “This image is a “balloon race”. The higher a bubble, the greater the evidence for its effectiveness. But the supplements are only effective for the conditions listed inside the bubble. We only considered large, human, randomized placebo-controlled trials in our data scrape – wherever possible. No animal trials. No cell studies..”
This visualisation generates itself from this Google Doc. So when new research comes out, they should be able to quickly update the data and regenerate the image. The spreadsheet also references the source of the research; if you’re interested in that sort of thing.
 

Man Babies {Misc-uity}

Do you need distracting? Or you might have too much time on your hands that needs filling…

Well here’s a little treat for those of you who’ve ever wondered what new fathers do on paternity leave. Click on the site to see plent more. ManBabies.com

ManBabies.com

Time-Lapse video of Eyjafjallajökull's plume {Misc-uity}

An incredible video by Sean Stiegemeier shot on a Canon 5D mkII. Describing his video he says “So I saw all of these mediocre pictures of that volcano in Iceland nobody can pronounce the name of, so I figured I should go and do better.”

Iceland, Eyjafjallajökull – May 1st and 2nd, 2010 from Sean Stiegemeier on Vimeo.

As It Occurs To Me {Radio}

Richard Herring returned to London’s Leicester Square theatre on Monday night to record the first in a new series of his stand-up and sketch show, As It Occurs To Me. Aided by comic actors Emma Kennedy and Dan Tetsell, with music from Christian Ryley, the show is, put simply, about whatever has occurred to Herring over the past week, whether they are things that have happened to him or his thoughts on things that have happened in the news. It shares a similar feel to his previous radio work, such as Fist of Fun and That Was Then, This Is Now, but because it is an Internet podcast, he can push the boundaries of comedy and decency as far as he’d like without having to worry about editorial interference or broadcasting guidelines.

For eight weeks, the show is recorded in front of a live theatre audience, who pay £10 each, which covers the costs of the production before the recording is released online, for free. It might seem a little odd to pay to see something which is then made available free of charge, but audience members get pretty good value for money. There’s a great atmosphere at the recordings which has seemed to be improving week by week, with final episode of the first series having a real party feel. But also, something new for this second series is that Herring opens with an exclusive 45 minute stand-up set, not available in the podcast, where he interacts with the audience, tells stories from some of his previous stand-up shows and mentions things that didn’t make it into the main show. This week, the audience was told of his experiences of being heckled by an octogenarian at the British Library and the time he wrote his “first book”, when he had a job inputting names and numbers into the BT phone book database, and changed his flatmate’s name in the listings to “Stewart Wee”.

The style of humour is very similar to the best of Lee and Herring’s work. On the surface, much of it is puerile, adolescent and often offensive, but always knowingly so. But it’s the anecdotal comedy that works best, like the story of meeting Scream actress Neve Campbell to discover that she “didn’t know how to pronounce her own name” or the discovery of an old notebook full of stories written by the a nine year old Richard Herring. Also, like Lee and Herring’s work, a lot of the humour comes from repetition, something which is regularly signposted. Favourites from the first series included the show’s only sound effect, a roulette wheel, which made it’s way into every episode, and “Tiny Andrew Collins”, Tetsell’s version of the broadcaster Herring shares his other podcast with, who isn’t a million miles away from Kevin Eldon’s Rod Hull character from Fist of Fun. The new series starts with Herring promising to drop all of the old catchphrases and running gags, but you can be sure that they’ll make a reappearance.

Herring writes the show within 48 hours of the performance. While it’s quite a feat to produce eight fully-formed comedy shows over such a short space of time, it’s just one sign of his prolificacy. As well as AIOTM and the Collings and Herrin podcast, he has been writing a daily blog for the last eight years, recently published a new book, been filling in for Adam and Joe’s BBC 6music show, just finished touring his excellent Hitler Moustache show, is about to bring a new version of his Christ on a Bike stand-up show to Edinburgh and is, occasionally, allowed on the telly.

The first episode of the new series is available now and is worth a listen if you’re not averse to very strong language. It includes the story of the cast’s night out at the Sony Radio Academy Awards, for which the podcast was nominated, which apparently turned out to be a moneymaking ruse by “Ian Sony”, plus a moving and not at all depraved tale of love between one man and one talking hotel lift. If you enjoy it, then it’s worth coming down to the Leicester Square Theatre and joining in the fun.

As it Occurs to Me is available on iTunes or to download from The British Comedy Guide

by Blake Connolly

Under Pressure {Ceri's Column}

I do love a game of poker. It really does grab you by the balls and holds you close saying: “Yeah? Yeah?! You think you’re so fucking hot, huh? Punk ass?” Well, that makes it sound like a violent pimp, but you get my drift. No? OK: Poker is awesome.

Mind you, I’m not great at the suspense side of it. I get all screechy when I’ve gone all in (chucked all your chips away) and are awaiting the river card (the last one they flip over and the American commentator of late-night Channel 4 poker shows calls out “Holy Yowza! If that ain’t the darnedest 3 hole strip-lined dandy river I ever saw!”…or something). I can’t bloody stand it!

It’s odd. I’m fine with scary films. I’m a picture of serenity with any real-life danger. Even sporting pressure is OK, (I played rugby for many a year until I got ill…and shit at it). But in the context of a game? I really am useless.

I’ve been known to stand up and shout: “WILL YOU FRIGGING HURRY UP AND TURN OVER THE CARDS YOU DIRTY ASSSSSHOOOOOLEEEE” at the poor, defenceless dealer! Well I say “defenceless”. I was escorted out of the casino by a burly security guy…who was wearing the same uniform as the croupiers. I hope he wasn’t a croupier…anyway, as per usual, I digress.

Come to think of it, I’m rubbish in other suspense-filled games.

Jenga? Jesus wept; I’m a nervous wreck… The thought of being responsible for a whole structure just tumbling down brings me out in hives! I stay clear of any game that even looks like it’s primarily made from wood now.

Buckaroo. It’s the bastard’s face. He looks so stressed! There is nothing worse than staring at an angry donkey carrying random objects.

Kerplunk? Fuck off.

So, by all means play me at Scrabble. Or Monopoly. Cluedo (or Clue to you Yanks) is a bit of a grey area. Hmmm. Better stick to I spy.

by Ceri Phillips